Drug Receptor (Pharmacology)

Drug Receptor in the Human Body:::

Property	Ligand gated ion channel (LGIC)/ Ionotropic receptor	G-protein coupled receptor (GPCR)/ Metabotropic receptor	Enzyme linked receptor (ELR)	Nucleic acid receptor
Location	Membrane	Membrane	Membrane	Intracellular nucleus
Sites of drug receptor interaction	Extracellular, intracellular	Extracellular, intracellular	Extracellular	Cytoplasm or nucleus
Effectors	Ion channel	Enzyme or channel	Enzyme	Gene transcription
Coupling	Direct	G-protein	Direct	Via DNA
Time of response	Millisecond	Second	Minutes	Hours
Example	Fast neurotransmitter, GABA, Glutamate, 5 HT3	Slow neurotransmitters, Neuropeptide	Insulin, Growth factor receptor	Steroid, thyroid retinoic recepto